Our super simple Lettuce Sandwich doesn’t get any easier than this! Perfect for an on-the-go lunch or gluten-free alternative!

The Best Lettuce Sandwich
This Simple Lettuce Sandwich is going to be your new go-to lunch idea! I am sure a lot of you have used “lettuce buns” to make a hamburger (like our Whole30 Garlic Burgers), but have you ever used it to make a quick and easy sandwich? It is my go-to when I am really in a pinch for a quick lunch or need something on-the-go!
Looking for More Sandwich Recipes?
If you love them as much as we do, you definitely need to try our Greek Sandwich!
Substitutions
- Deli Meat – feel free to use of your favorite deli meat options from the local grocery store.
- Mayo – make sure to grab a Whole30 compliant option, if you want, or another regular mayo, if that isn’t a concern.
How To Make A Lettuce Sandwich
The first steps to making this easy recipe are to set the head of iceberg lettuce on its side and cutting “buns” off the sides – see pictures below!

First, you cut off a slice for one of the buns.

Then cut off another slice for the second bun! You should be able to get up to 4 buns (depending upon the size) out of one head of lettuce. Save the leftover lettuce for a salad!

Spread a generous amount of mayo on the inside of the buns and add any of your favorite sandwich fillings.

Can I Make Lettuce Sandwiches Ahead of Time?
Yes! Option to make these the day before and store in the refrigerator for the next day!

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Lettuce Sandwich Recipe
- Prep Time: 10 minutes
- Cook Time: 0 minutes
- Total Time: 10 minutes
- Yield: 1 serving 1x
- Category: Lunch
- Method: Counter Top
- Cuisine: American
Description
Our Lettuce Sandwich is an incredibly easy lunch or dinner idea! They are so good and so simple to make with any fillings you want!
Ingredients
- one head of iceberg lettuce, outer 2-3 pieces removed and rinsed clean
- mayonnaise
- 1–2 slices of red onion
- 3–4 slices of deli meat
- 2 slices of tomato
- optional: homemade guacamole or avocado slices
Instructions
- Lettuce Bun: Take the head of lettuce and lay it on a cutting board; use a large knife to cut off two slices from the lettuce to create buns (see photos in post for an example).
- Mayo: Take one of the lettuce buns and add as much mayo as desired.
- Add Fillings: Top with red onion, deli meat, tomato, and guacamole (if desired).
- Serve: Place the other lettuce bun on top and enjoy!
Notes
- Whole30/Paleo: check ingredients of the mayo to ensure it is compliant or make a Whole30 homemade mayo. Also, check the ingredients of the deli meat.
- Meal Prep: You could definitely make these sandwiches the day before work and store in the refrigerator overnight in an airtight container. If you want to store for longer, then I wouldn’t add the mayo or guacamole until ready to eat, so the lettuce doesn’t get soggy.
Nutrition
- Serving Size: 1 Sandwich
- Calories: 306
- Sugar: 19.9 g
- Sodium: 814.9 mg
- Fat: 12.2 g
- Carbohydrates: 28.9 g
- Fiber: 10.4 g
- Protein: 25.9 g
- Cholesterol: 42.8 mg
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